ABSTRACT
Squamous cell carcinoma [SCC] is one of the most common malignant tumors of the lips [90%]. The prognosis of these SCC seems to be poor thus here periorificial localization. To present the epidemiological, clinical, pathological, therapeutic features and out come of SCC of the lips. We conducted a retrospective study performed in the dermatology department of the La Rabta hospital of Tunis over a 11-year-period [2000-2010] recording patients with histologically confirmed SCC of lips. Thirty patients were included [26 men and 4 women] with an average age of 63 years. The most frequent risk factors were smoking and chronic sunlight exposure. The occurrence of the labial SCC on a precursor lesion was noted in 11 cases. It occurred more frequently on the lower lip [80%]. Tumor was ulcero-vegetant in 21 patients. Twenty patients had a commune SCC, 19 of them were well-differentiated. Surgery was indicated in 18 cases and 10 patients were treated by exclusive radiotherapy. Lymph nodes metastases were noted in 2 cases. No visceral metastasis was observed. During the period of follow-up [20.12 months], two patients died. The diagnosis of SCC of the lips is late and the treatment often mutilating. The improvement of the prognosis depends not only on the early diagnosis and the treatment of the precursors, but also on the photo protection and alcohol and smoking eviction
Subject(s)
Humans , Male , Female , Carcinoma, Squamous Cell , Lip Neoplasms/pathology , Lip Neoplasms/therapy , Risk Factors , Retrospective StudiesABSTRACT
Extramedullary plasmocytoma is rare, with less than 50 reported cases and only 8 cases of primary testicular plasmocytoma. Report of a new case. This report concerns a 65 years old patient presenting an enlargement of the testis. The diagnosis of testicular plasmocytoma was made on histological examination. There was no evidence of bone marrow involvement or systemic signs of myeloma. This case will be studied with a review of the literature
Subject(s)
Humans , Male , Testicular Neoplasms/pathology , Multiple Myeloma , Review Literature as TopicSubject(s)
Humans , Male , Gastrointestinal Stromal Tumors/diagnosis , Hematemesis , ImmunohistochemistryABSTRACT
Background: Primary testicular lymphoma is the most common testicular malignancy in the elderly, account for 1% of all non Hodgkin lymphoma [NHL]
The aim was to report from new cases of testicular lymphoma
Cases: We report the only four cases of testicular lymphoma observed in a period of 15 years; all these cases were primary diffuse large cell B NHL. Disease course is usually aggressive, with widespread organ involvement. Retrospective analyses show a poor prognosis for this presentation
Subject(s)
Adult , Aged , Humans , Male , Middle Aged , Retrospective Studies , Lymphoma, Non-Hodgkin , PrognosisABSTRACT
Neuro-endocrine tumors of the pancreas are rare. Tumors can be discovered according to the endocrine syndrome produced. They are characterised by a slow evolution. Criteria of malignancy are metastasis to lymph node, liver or dissemination to other organs. Occurrence of multiple neuro-endocrine tumors may be seen forming multiple endocrine neoplasie type 1 or MEN-1
Subject(s)
Humans , Female , Nose Neoplasms , Exophthalmos , Neurilemmoma/pathology , Neurilemmoma/surgeryABSTRACT
Hyperplastic polyposis is a loosely defined syndrome initially thought not to confer a clinically important predisposition to colorectal cancer. However, number of reports have been made of individuals with this condition who have developed colorectal carcinoma. We report here the case of a 60 years old woman with adenocarcinoma of the rectum who underwent a right hemicolectomy. More than 50 sessile polyps where found. The histologic examination revealed the hyperplastic nature of these polyps. One of them was a serrated adenoma. Hyperplastic polyposis is rare and is associated with an increased cancer risk. The patients need to be followed with successive endoscopies